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Dean was diagnosed IMHA in May right before mother’s day weekend :( He was showing signs of being lightheaded and falling over. Tests showed normal heart and abdomen but extremely low red blood cell count that dropped dramatically over the course of a week. He received a blood transfusion and slowly showed signs of improvement over the next three months. Now, blood test results are showing some dramatic changes again and after reading up on the risks of a blood clot during a blood transfusion, I don’t want to put him through that again. However, I can’t resign myself to just finding ways to keep him comfortable until he passes. As a last resort I discovered articles about Traditional Chinese Veterinary Medicine (two practitioners in my area) and the use of Bio-Algae Concentrates. Has anyone had experience or gotten professional consultation on these alternative methods? We have an appointment next week with a TCVM doctor and I’m trying to get as much information as I can beforehand.
Hi Amber
Glad you’ve found our site – I’m so sorry you’ve had to go through this with Dean. We are committed to giving you only the proven facts on here, so forgive me for being blunt. I’m afraid we are unable to find any proof or clinical trials to show that this Bio-Algae product works for our IMHA pets – we have looked at this in detail, I assure you. As IMHA is an auto-immune disease, it is certainly not advisable to stimulate the immune system with this kind of product. I would advise against using it most strongly. I would never use it for my dog.
If you can provide us with more information about Dean, we will gladly help you with the conventional treatment options. Tell us exactly what happened, what drugs he was given at diagnosis & what he is taking currently. There is no reason why Dean cannot make a full recovery & be back to normal health with the right care. You would be very welcome to join us – I hope you will!
Sheena
Hello Amber,
I am sorry your Dean is not well and you are going through all these health issues with him for 3 months now. In order to help you more and advise you on what to do, it would be important to know more about Dean. What are his latest blood results, what medications is he on, his weight, age, breed, any supplements. I would not worry about a transfusion unless his PCV is going down to at least 15%.
I am a big fan of holistic and TCM. However with this disease I believe that TCM can only be complimentary. Some of the herbs given could also totally work against what you are trying to achieve. For example many herbs boost the immune system, while you are actually suppressing it to stop the body from attacking the red blood cells. This is also the case with Bio Algae. This product has come up here many, many times and in my opinion (and all of the other moderators) it gives you false hope and is very expensive. There are no studies that it helps with AIHA/IMHA. It claims to boost the immune system, something you want to avoid at all cost. There are many herbs that help with this disease, one of them is milk thistle. It helps the liver to detoxify and keep up with all the heavy duty medications that these dogs need to survive. I know it is hard to see all the side effects of the drugs, but in the long run they will save Dean’s life. It would be good to know if you have reduced the drugs (prednisone) and maybe that happened too fast? You could download Dean’s latest blood results under Urgent Advice. The moderators will get this in their emails can have a look at it and hopefully advise you.
I don’t say don’t go to a TCM vet but please have the two vet’s work together so they are both aware what is happening. Please do not buy Bio Algae it is money down the drain. If you want the best of the best, consult with Dr. Dodds at hemopet. You find all the information under Second Chance Resources. You can get a detailed consultation from a vet that has treated this disease successfully for many years for a reasonable fee.
Best wishes,
Brigitte
I rescued Dean from a shelter when he was only about 3 months old. Our best guess at his breed is “Shepherd Mix” but there are a lot of Golden Retriever features to him. He is now almost 4 years old and weighs 50lbs.
It feels like Dean has been on a lot of medication for a long time. After the blood transfusion these were his medications: Prednisone 20mg 2.5 tablets given once daily, Cyclosporine 50mg 2 capsules in the morning and 1 capsule in the evening, Omeprazole 20mg tablet once daily, Clopidogrel 75 mg 1/2 tablet once daily. He was also on Doxycycline and Vitamin B12 before the transfusion but they had no effect. He also received an iron dextran injection prior to the blood transfusion. The Clopidogrel was the first to be discontinued along with the Omeprazole. We have been decreasing the Cyclosporine by 1 capsule a month pending improved blood tests. Three weeks after his last dose of 50mg Cyclosporine, his blood tests started to decline so he is back on 50 mg Cyclosporine daily. Prednisone has not changed.
He received an ultrasound that showed no internal bleeding and wore a holter heart monitor for 72 hours to rule out seizure related disorders (since he was falling over and a couple falls looked like “pre-seizure” activity). However, his fur has not grown back since being shaved for these procedures in May. The vet also noticed that his skin is very dry and yet another blood test revealed that his Thyroid is not functioning properly and we are now on Soloxine .5mg daily.
His blood tests don’t show the red blood cell count as a percentage but according to the last test the result was 4.51 whereas the Adult reference Range is 5.50-8.50. I read in another post about using fish oil to manage the side effects of Prednisone so I bought some of that today. I will also look into the milk thistle and try to upload some of his tests.
Also, thank you for all of this information and for your quick response. I’m so glad to have found this group and look forward to gaining more insight from everyone.
Hi Amber, and welcome to the site. Just running in and need to run out again, so I’ll be back. First of all I’m glad Soloxine has been started. That seems to be the magic ingredient that puts it all together so I’m hoping that does the trick for Dean.
Just make sure it’s given at least 1 hour before food or 3 hours after food. I know that’s hard sometimes with all the drugs, but otherwise it’s not really doing anything.
I’d be happy to make up a chart.
Need to run. I’ll post again shortly.
My best,
Vally & Bingo (diag Nov 2011, in remission)
Hi Amber, welcome to the group and I’m sorry you have to find it. From what you’ve said, your drs may be trying to reduce the meds too quickly? Are you doing big drops each time did you try to go from 50mg of Cyclo to nothing & were other reductions handled this way? The thing with this illness is that reductions need to be done as slow as the body allows – if there are not very adverse effects, go slow. Once a month is good, but if it’s a big drop each time that isn’t.
I didn’t use Cyclo so I am not very familiar with the reduction protocol, but pred-azathioprine should be reduced around 25% no more than every 2-3 weeks following stable test. Sadly, a lot of vets try to follow “normal” protocols for reducing these drugs, calling for 50% reductions at a time or abrupt stopping, which in most other cases is fine but not so with an AIHA dog. You almost have to trick their body into not realizing you are doing it, or relapses are highly likely. I had to seriously fight with my vet to follow a different protocol than she wanted, and it was so bad I eventually switched clinics. If this is what your drs have done, please don’t blame yourself and don’t worry. You can help Dead through this, there is no reason to give up. If his blood shows any signs of clotting, he can be put on an ultra low dose of aspirin to help. If he needs a second transfusion, I would encourage you do to so and slow way down with medication reductions once he is again stable.
Have you ran a full chem panel? How is his liver, kidney? What side effects is Dean having from the pred? Milk thistle & sam-e are highly recommended to aid the liver through all these horrible meds. It also comes in pill form called denamarin. It is expensive, but will work to help the liver, and would be easier to manage if Dean is easy to give pills to. Muscle wasting, weight gain and frequent urination sadly can’t really be helped while on Pred. A lot of our dogs get nasty skin and UTIs during treatment, too. All of this is common and treatable.
If Dean is relapsing and I misunderstood your post and the reductions haven’t been large ones, you may need to look at the environment and try to figure out if something is causing this. Have you sprayed any chemicals? Have your neighbors? Do you live in an area that sprays for mosquitoes? Are you giving heartworm/flea meds, if so what kind, and how often? When was Dean last vaccinated & for what & what kind (pro heart 6, etc?) Were there any major changes in Deans life around the time he started to relapse that may of really stressed him out (someone moved out, anything like that?). Has he had any fleas or ticks, and has he been tested for tick borne illness? There are so many triggers. If you can FIND what is causing it, that is great, but a lot of times you will never know. But you should scrutinize his immediate area and see what you can find. How are Deans appetite and energy levels?
These ladies here will help Dean and you through this. My dog, Sassy, was diagnosed with AIHA in March and I was so low until I found this group. Ask ANY question, even if you think it is silly. And every little bit of information you can provide would be great. Please also scan/take a photo of Deans test results and send them via ‘urgent advice’ up top, and the ladies that are good at reading the test will get right on them!
Thank you Alyssa. Dean is easy to give medicine to as long as peanut butter is involved. He was overly hungry and even licking holes in the carpet before we tested his thyroid. I also started giving him lots of carrots and green beans to help with this. I will ask the vet about his liver. She has been consulting with the specialist at the clinic where he received his transfusion. I do think we jumped off the cyclosporin too soon but he is back on it now and the vet said this could be the case since he was so slow to respond to treatment in the beginning. I can’t think of any possible environmental cause for all of this. After reading other posts I’m considering changing boots diet from Rachel Rat’s line to something all natural. He was on nitro and blue buffalo in the past but they both upset his stomach and he would frequently spit up a yellow/foamy bile in the mornings. OTC acid reducer didn’t help. Do you have any recommendations dog food?