Stem Cells?

[Amy]

http://www.metrovetchicago.com/services/stem-cell-therapy/

[Sheena]

Interesting – info is exactly the same as
http://www.vvhcny.com/newpage101.pml

Doesn’t tell us much at all, but both quote Medivet.

Did you watch the video ? – I quote “and one day soon, internal medicine problems” so we are maybe a bit early just yet. Will e-mail them tomorrow – let’s see if we can get more info.

[Meg Lewis]

HI I’m actually doing a little research for a friends dog…. that was just diagnosed today with IMHA … I actually do stem cell for my black tri aussie , she has SA (sebaceous adenitis) which is loosely explained by her own body is killing all her sebaceous glands causing her to lose hair and the dry cracked skin is then open to secondary infection of Staph or MRSA…. I pushed hard for stem cell and if it hadn’t been for my veterinarian going to UCDavis and had a collegue doing stem trails … I have to say i’m forever grateful!! the stem cells are harvested from her umbilical area and only the cells that are not damaged are then replicated in the lab… ( please don’t believe that this can be done in office… you must go with a reputable lab.) I store the cells so no additional surgery is needed. This is not a cure…for this particular Auto immune disease … we do an infusion yearly…. I’m a veritable data base of information!! i’m excited to see people interested!! If you would like more info don’t hestitate to ask… ! I will be contacting VetStem for information for my friend!!

[chris kim]

my dog has IMHA and is currently on immuno-supressants and going through blood transfusions. she hasnt eaten in 4 days so they are doing a nasal tube to feed her. i asked the doctor what she thought about stem cell fusion and she said it wasn’t recognized in the scientific community as a cure and highly discouraged it. a stem cell facility in texas said that stem cell transfusion attacks the source so the quicker the better. My question is, what are the risks of doing stem cell transfusion? could this lead to death and complications? can someone go into detail on this?

[Vally]

Hi Chris, I’ve had no dealings really with stem cell treatment for AIHA, other than the post you have found here.

Can I refer you to Dr Jean Dodds perhaps. She is brilliant in this disease and has helped many of our dogs here. If anyone is up to date on stem cell work for AIHA dogs, it would be her.

We have a link to her site from here, but it’s not happy right now. You can try here:
https://www.hemopet.org/holistic-care/online-consultations-with-dr-dodds/

If you decide to go with drug therapy, happy to help you any way I can.

My best, Vally

[Patrice]

Chris,
I’m wondering if you could explain a bit more of the details of your dog’s diagnosis. What signs led you to seek treatment? What was the diagnosis in more detail.

What can you provide me in details from the current CBC and CHEM screen?

Treatments for IMHA have more recently become standardized and smarter in the last 5 years. Vet clinics are beginning to use protocols that address using a cocktail of immunosuppressive drugs and supportive supplements that provides a quicker reduction of hemolysis. Also they stabilize the patient by using drugs that reduce the risks of inappropriate and dangerous clotting such as low dose aspirin or heparin etc. This last part is always concerning as the risks of a dog becoming unstable during rapid hemolysis can lead to a clotting emergency.

So I’m not sure exactly what the stem cell treatment entails. Now if this was actually non regenerative anemia due to bone marrow failure, there might be some researchers who have experimented with some sort of stem cell transfusion.

However, most cases of canine bone marrow failure show up as non regenerative anemia due to an autoimmune attack to the precursor cells deep in bone marrow, which does often respond to these sophisticated clinical protocols. These precursor cells might also be thought of as similar to stem cells. Either is a type of blank cell that is prepared to become one specific type of cell.

So I am thinking that perhaps this is what you are trying to describe to me?

The most important element for out of control destruction of red blood cells is that this is an attack “on self” or the inability of the immune system to recognize “self.”

There can be, and usually are, multiple triggers, usually 2-5, that form together as a tipping point that leads to an attack on self. Those need to be identified as thoroughly as possible in case they are treatable. So think back and try to remember signs like this. Were there allergies, digestive upset that never resolves, exposure to bites or stings, recent vaccinations, drugs administered, viral disease or bacterial disease such as tick bite diseases or leptospirosis, doggie flu, urinary tract infections, an older dog might have an internal tumor, a younger dog may have eaten something dangerous.

If you have always trusted your vet, simply ask them why they are using the treatments they are. If you are uneasy you can always get a second opinion from another vet, that’s acceptable.

Give me a bit more information so i can help you.
My best Patrice

[Jenn S]

See Dr Steve Garner’s paper at SafariVet. He has done extensive treatment with allogenic stem cells with IMHA dogs. My personal dog was treated with 4 treatments and saved his life when TPE and 9 transfusions and immunosuppressives were seemingly futile. He has a paper on this as well. Cost is $1000 and $250 overnight shipping last time ai checked. Worth every penny at least for regenerative anemia cases, non-regenerative can be unpredictable or more guarded.

[Amy]

http://www.metrovetchicago.com/services/stem-cell-therapy/

[Sheena]

Interesting – info is exactly the same as
http://www.vvhcny.com/newpage101.pml

Doesn’t tell us much at all, but both quote Medivet.

Did you watch the video ? – I quote “and one day soon, internal medicine problems” so we are maybe a bit early just yet. Will e-mail them tomorrow – let’s see if we can get more info.

[Meg Lewis]

HI I’m actually doing a little research for a friends dog…. that was just diagnosed today with IMHA … I actually do stem cell for my black tri aussie , she has SA (sebaceous adenitis) which is loosely explained by her own body is killing all her sebaceous glands causing her to lose hair and the dry cracked skin is then open to secondary infection of Staph or MRSA…. I pushed hard for stem cell and if it hadn’t been for my veterinarian going to UCDavis and had a collegue doing stem trails … I have to say i’m forever grateful!! the stem cells are harvested from her umbilical area and only the cells that are not damaged are then replicated in the lab… ( please don’t believe that this can be done in office… you must go with a reputable lab.) I store the cells so no additional surgery is needed. This is not a cure…for this particular Auto immune disease … we do an infusion yearly…. I’m a veritable data base of information!! i’m excited to see people interested!! If you would like more info don’t hestitate to ask… ! I will be contacting VetStem for information for my friend!!

[chris kim]

my dog has IMHA and is currently on immuno-supressants and going through blood transfusions. she hasnt eaten in 4 days so they are doing a nasal tube to feed her. i asked the doctor what she thought about stem cell fusion and she said it wasn’t recognized in the scientific community as a cure and highly discouraged it. a stem cell facility in texas said that stem cell transfusion attacks the source so the quicker the better. My question is, what are the risks of doing stem cell transfusion? could this lead to death and complications? can someone go into detail on this?

[Vally]

Hi Chris, I’ve had no dealings really with stem cell treatment for AIHA, other than the post you have found here.

Can I refer you to Dr Jean Dodds perhaps. She is brilliant in this disease and has helped many of our dogs here. If anyone is up to date on stem cell work for AIHA dogs, it would be her.

We have a link to her site from here, but it’s not happy right now. You can try here:
https://www.hemopet.org/holistic-care/online-consultations-with-dr-dodds/

If you decide to go with drug therapy, happy to help you any way I can.

My best, Vally

[Patrice]

Chris,
I’m wondering if you could explain a bit more of the details of your dog’s diagnosis. What signs led you to seek treatment? What was the diagnosis in more detail.

What can you provide me in details from the current CBC and CHEM screen?

Treatments for IMHA have more recently become standardized and smarter in the last 5 years. Vet clinics are beginning to use protocols that address using a cocktail of immunosuppressive drugs and supportive supplements that provides a quicker reduction of hemolysis. Also they stabilize the patient by using drugs that reduce the risks of inappropriate and dangerous clotting such as low dose aspirin or heparin etc. This last part is always concerning as the risks of a dog becoming unstable during rapid hemolysis can lead to a clotting emergency.

So I’m not sure exactly what the stem cell treatment entails. Now if this was actually non regenerative anemia due to bone marrow failure, there might be some researchers who have experimented with some sort of stem cell transfusion.

However, most cases of canine bone marrow failure show up as non regenerative anemia due to an autoimmune attack to the precursor cells deep in bone marrow, which does often respond to these sophisticated clinical protocols. These precursor cells might also be thought of as similar to stem cells. Either is a type of blank cell that is prepared to become one specific type of cell.

So I am thinking that perhaps this is what you are trying to describe to me?

The most important element for out of control destruction of red blood cells is that this is an attack “on self” or the inability of the immune system to recognize “self.”

There can be, and usually are, multiple triggers, usually 2-5, that form together as a tipping point that leads to an attack on self. Those need to be identified as thoroughly as possible in case they are treatable. So think back and try to remember signs like this. Were there allergies, digestive upset that never resolves, exposure to bites or stings, recent vaccinations, drugs administered, viral disease or bacterial disease such as tick bite diseases or leptospirosis, doggie flu, urinary tract infections, an older dog might have an internal tumor, a younger dog may have eaten something dangerous.

If you have always trusted your vet, simply ask them why they are using the treatments they are. If you are uneasy you can always get a second opinion from another vet, that’s acceptable.

Give me a bit more information so i can help you.
My best Patrice

[Jenn S]

See Dr Steve Garner’s paper at SafariVet. He has done extensive treatment with allogenic stem cells with IMHA dogs. My personal dog was treated with 4 treatments and saved his life when TPE and 9 transfusions and immunosuppressives were seemingly futile. He has a paper on this as well. Cost is $1000 and $250 overnight shipping last time ai checked. Worth every penny at least for regenerative anemia cases, non-regenerative can be unpredictable or more guarded.