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- Milo diagnosed with IMHA 9 days ago.
Thanks for the reply Patrice! The emergency vet did do a great workup and I am so great full we had access to them, but it has been pricey. They did ask or bring up all of the possibilities you mentioned. It is so frustrating not knowing what caused all this devistation in our lives. Good thing is Milo has always been incredibly healthy…no illness, no allergies. I credit this to his Heinz 57 pedigree! We live in Texas, outside of Houston. Our property backs up to a bayou and nature trail. We have seen more venomous snakes this year than in previous years, however I have not seen any evidence of bites. When we first moved in (15 years ago) ticks were a huge problem. I would find ticks on our dog daily. I have not seen any on Milo but I know that doesn’t mean anything. Also he had his yearly vaccines two months prior to his diagnosis. It COULD have been any of these and honestly we may never know. The vet said there was a panel they could send out to look for more of the tick born diseases that were not covered, but as long as he is responding to treatment I just don’t think the expense is justified. I don’t believe it is a food issue. We only feed dry food and his brother Toby has had no issues.
Kisha,
I’ve been on a private tick discussion group since 2007 and have picked up a lot of information about tick disease. There are a few tick diseases, and one in particular, that can hide out for years and return much later with a vengeance. The dog can have a brief illness and then much later present with sudden serious symptoms that can lead to death. I am never truly convinced that it is appropriate to disregard previous tick bite history. I have helped owners whose dogs were in these last stages and it was very difficult to watch these dogs crash so quickly. The owners could not understood how a tick bite a year ago could do this. Nor did they understand that many vets fail to treat the original tick bites with the proper dose of doxycycline, or as we say, “only tickled the tick,” allowing it to hide where it couldn’t be affected by the medication.
On this page, click on Tick Borne Diseases and Dogs.
https://www.secondchanceaihadogs.com/parasite-resources/
Gil has spent years collecting and modifying this information. Click on the picture of the page to open the site in a new tab. You can read many of the pages if you wish but it might be good to start by reading her information about Erhliciosis, click on that page in the right sidebar. She discusses the three stages of the disease, the last often happening much later.
I am merely trying to encourage you to not discount further testing for tick diseases, not scare you. In a dog that has very few risk factors this is still an unknown as far as I am concerned.
The other page you may want to consult is the Test Laboratories. I recommend ProtaTek. This is all that Dr. Holland and her staff do, test for tick diseases and other like conditions. She is always willing to discuss things with a vet on the phone. The main issue comes down to the difference between a screening test (is there some indication of infection at some point in time) vs a test that measures titers (how much infection is there.) It’s not quite that simple, but when you are looking at a disease that can hide in the body you want to be able to measure “how much” not just yes or no.
When Chance was so very ill in 2007, these were the first tests I had run, I was hoping to God that it was a tick disease and we could treat it with doxycycline. It wasn’t, as Dr. Holland explained to me, the titer was extremely low and could be explained as an aberration. She’s good with these tricky lab results.
As for dry food, Dr. Dodds would be the first person to note that dry food can be tainted with dangerous microscopic molds like and fungus like Aspergillus which may cause serious illness. I would never assume any dried dog food is perfectly ok.
I would like to see a chem screen from any time during this diagnostic period, this is the test that looks at the functions of the body such as the health of the organs, blood sugar etc. I am looking for a specific reading. You will know you have done one because it can be very expensive, more so than the CBC I was able to look at. Thank you.
Perhaps you can tell me more about the actual day you felt he was ill and how he behaved when you thought this. That would be very revealing. We should try to tease this out a little bit more for your sanity.
my best
patrice
Good morning…and it is a good morning!! We took Milo in for a recheck of his PCV this morning and it is up to 28!! that is a 10 point increase in 4 days! I know we are still not out of the woods but it sure is an answered prayer!! Milo is still really struggling with nausea/vomiting/lack of appetite. I know it is a result of the meds that are saving his life, but it sure is hard to watch him feel so cruddy!
Patrice,
thanks for all the input. I am not discounting any cause for all of this happening. It could well be tick borne as we do live in a part of the country where ticks are a part of life, I have not seen any around here in 15 years, and have never seen one on him, but some of them can be so small that you would never even be aware that they are there! Milo has been on 300 mg of doxy daily since all of this happened (and will continue on it for another 2 weeks) as the vet said that will cover MOST tick borne disease. If he had not responded, we would have (and still may) run the other tests.
As far as onset of symptoms, hind site is always 20/20! In looking back, I had noticed that he seemed a little less patient with his brother for a couple of weeks prior to when we took him in. He was a little snappier with him. Could be completely unrelated. On Sunday 7/9 in the evening he kept wanting to go out more. Would try to have a BM and was only having a small amount. No loose stools, but that was what the behavior reminded me of. The next morning, he refused his breakfast. (which is completely unlike him!!). I was leaving town for business and told my husband to keep an eye on him. I honestly just thought he had some gastric upset. Tuesday he was about the same, he would eat treats or people food but refused dinner. Tuesday night, my husband took both dogs out for their nightly walk and Milo went to the end of the street and refused to go any farther (also very unlike him as he LOVES his walks). They took him in first thing Wednesday morning.
There was a chem panel about midway through the attachments (I will resend in case it did not go through)
Kisha,
Thank you for the update and the chem screen!
The chem screen is completely normal. There are no values that are low normal or high normal. The value I wanted to check is globulin. Dogs unable to effectively fight ehrlichiosis in the early days of infection can become chronically infected. In that case we would have seen elevated globulin levels in the blood, which we don’t.
In addition, dosing with doxycycline can be prophylactic. This means that there was never a diagnosis or sign of tick disease but that there was the potential for exposure. So dosing with doxy “just in case” is often a very good approach with tick diseases. My vet is very much in agreement and if I find an attached tick on one of them, she is willing to dose with a prophylactic dose. Testing for tick diseases is not effective until approximately 6 weeks after a bite! Too long to wait if there was exposure to disease, it’s best to treat right away.
I misunderstood about his exposure. It sounded like there were times when he had ticks on him. Yes, there are small ones and they are very hard to find, so exposure can happen without ever seeing a tick.
In general tick diseases are spreading, esp due to climate change, at a rapid rate. Areas that had no reported ticks even 5 years ago are seeing them in greater numbers, for instance Canada. I keep track of reported tick disease with this website.
http://www.petsandparasites.org/parasite-prevalence-maps/#2017/all/lyme-disease/dog/united-states/
An owner can drill down through the maps to their own county and can also request a monthly email notifying of the reported cases of each tick disease in their area. CAPC is careful to point out that these are only reported cases and the numbers of disease are probably much higher if you consider all the dogs that went untreated or vets that didn’t report. So I have been seeing skyrocketing tick disease numbers in the location I live and vacation in. You might want to keep track of CAPC maps on your own, via their regular emails.
Many owners have remembered that their pet was acting sluggishly in the days before they truly noticed something seriously wrong, you are not alone.
A PCV of 28% is great! He’s moved very close to what could be considered moderate to mild anemia. So there is positive regeneration and apparently less or no more hemolytic damage occurring.
Whatever the trigger, it appears that he was uncomfortable. Dogs tend to have behavior changes when there is some degree of pain or discomfort. So something did happen, but what is not clear.
Please keep us up-to-date with future improvements and questions!
my best patrice
We took Milo in last Friday for a recheck. His PCV remained at 28. They did a chem screen and everything was within normal limits. Unfortunately, he is really not doing well. Frequent vomiting, refusing to eat, watery stool…he feels miserable. He lost another 4 lbs since the previous week, so has lost about 20% of his body weight since this started. We added Reglan to his regimen hoping to help his GI motility – which will make the diarrhea worse, but will hopefully help him hold food down. I feel like these meds that are saving him are also killing him. We made the decision to wean him down on the Atopica as most of his GI issues started after adding it. Ideally we would like to see his PCV still increasing and holding steady for a few weeks prior to decreasing, but I don’t feel like that is an option for him. At this point I honestly don’t know if he is going to make it and it is breaking my heart.
We took Milo in again today for a PCV check. His reading was 36, but the doctor feels that is a false reading due to some dehydration. He has lost 4 more pounds this week. He is down to 52 lbs. We still cant really get him to eat. We have added an appetite stimulant to the medication regimen and taken him off of the Atopica all together. Please add him to your prayers.
Keisha, first of all the drugs are doing their stuff to get the great PCV results.
I’m actually wondering whether the Mycophenolate may be the culprit in causing the gastric issues. Please read this
https://www.secondchanceaihadogs.com/AIHA_Terms/mycophenolate-mofetil/
Is Milo still not n this?
Vally
Good afternoon Vally! Yes, he is on mycophenolate, though we have reduced the dosage to account for his weight loss. We have stopped the cyclosporine completely. He is also done with the doxy. Sadly of the 6 meds he was on, 4 had gastro issues listed as the main side effect. We added mirtazipine for appetite stimulation and it has worked a bit (not as much as I would like) but he seems to be vomiting more since starting on that. We also added ranitidine to see if that will help. Like I said…the meds are saving him but are also causing all of his problems!