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- Split: Split: Nula (5yr old English Cocker Spaniel)
Hello all! Good news, I think! It seems that the low result was because of a clot in the sample. Because Nula was so well and the number so low in the quick test, they rechecked and did it 3 times to see why her behaviour and the number were at odds. That’s when it back at 39, which is what it was at the previous appointments results. And today’s result, after running it several times to make sure is 43!!! And her platelets are 504! She also had an eye test (her eye has had some clear jelly gunk in it) and she has near perfect vision and the gunk is fine. So that’s good too. She was really good at the vets today. And I asked, and they always take blood from the neck, unless there’s a good reason not to. So the plan is to drop her prednisolone slowly over the next month and test again 1st July. They said that it takes a while for the lower dose to take effect hence wait a month. Does that sound right to you guys? I feel a bit more confident about doing it slowly, and feel better about the results and have more confidence in them. So we’ll see how reducing slowly to 20 x daily and I’ll keep a close eye on her gums etc. Atopica stays the same. What are your views? I hope you’re all well and four legged babies are all happy and well! Thank you all so so much for your support and advice!!!!! Xxxxxxxx
Hi Ruth
Wow! Lovely results – I like the PCV of 43 very much (and the normal platelet count assuming that’s 105/µl³) & that guilty clot explains the strange differences previously. BUT Now I’m very confused! – I thought you said Nula was on 15mg pred twice daily? But now she’s on 20mg twice daily? Did you put it up when the last result was iffy? Sorry to ask more questions! Anyway whatever she’s on it looks good – I know you’ve got the hang of this now & you know exactly what to do- if you stick to a 20-25% prednisolone reduction per month, as that is considered a nice “conservative” reduction for AIHA/IMHA. Get a blood test immediately before & a week after each reduction & constantly check gums & the way she acts & the theory is that all should be well. If she can’t get off the pred completely, it doesn’t matter one little bit, as long as she’s stable. Some dogs (not all) need a very low maintenance dose, but what the heck? And leave the Atopica as it is until the prednisolone is either nil or very low. I am so happy for you Ruth – you’ve been brilliant with sticking to your guns & you have done the best anyone could ever do for Nula. I think a little celebration is in order – an extra biscuit or two may be called for, plus Mr Sheepy playtime. Congratulations! I am thrilled to hear the good news.
Love Sheena, Worzel & Ollie xxxx
Oh congratulations Ruth – of course you too Nula, after all you did all the hard work. That wonderful news.
Yes you might want to clarify what Nula was taking and is now taking. I’d probably have her PCV checked after you actually do the drop. I’m not too sure I’d wait until a month before testing. We just always checked straight after a drop in prendisone in the early days.
Yes certainly worth a celebration after all the worry.
Love Vally & Bingo
Hi Ruth,
I am really happy that this PCV is this high! Wonderful news! You must be beside yourself with relief.
I am, however, peeved about the mistakes with the blood sample. This happens far too often. In a healthy dog, an odd number is clearly a mistake and most vets won’t say anything about it. In a dog whose medication dosages are determined by the results of these tests, it is inexcusable for them not to take great care with these tests.
May I suggest that you do a few things to you to make this situation better?
Make sure that Nula has fasted about 8-10 hours before the test but make sure she is well hydrated, provide lots of water. Trying to get a good blood sample from a dehydrated dog can actually damage the sample, leading to these kinds of problems. Dehydration can skew the results, changing the percentage of some things incorrectly. The red blood cells can also bang against each other due to the slow tube fill and burst causing clotting. Eating too close to the time of the test will increase the number of fat molecules in the blood. These can cause aberrations in the sample that the automated laser will have trouble seeing through. The sample would be referred to as lipemic.
Schedule a time when you know the clinic will be quiet. Try to avoid any stress to Nula. Dogs react to many situations by being over-alert. This can cause changes in the blood that can skew the results as well. If you can, try to get there really early in the morning when it is quiet and she is sleepy.
Always politely ask to be with Nula when they do the blood draw. Be abnormally quiet and reserved so she will not reflect your nervousness. I actually sit on the floor with my dogs petting them and singing to them quietly to relax them.
Carefully observe the behavior of the techs that take the samples. If they are nervous and fumble, seem to not be sure what they are doing, remember their name. When you find a tech that is good and that Nula likes make sure you get their name. When you schedule the next appt ask for her/him. Say whatever you have to in order to make that happen but always be polite and respectful, “oh Nula loves Sam so much, is there any chance she will be available to do her blood sample on thursday morning?” Be agreeable to changing your schedule to have that tech.
Never leave your dog alone with the staff when you are there. Be extremely polite, but nicely insist that you are with her. Say something like you are studying how something is done and you want to watch or be profuse about admiring how clever the tech is. Just make it happen.
This is the only way you are going to find out who and how these samples are getting goofed up. A sample needs to be taken carefully and efficiently, the sample tube needs to be handled carefully, it needs to be taken care of immediately. In all three cases it will clot abnormally.
If you are suspicious, don’t make a big fuss with that tech but in a bit mention you need to talk to the vet before you leave. Be polite to the vet but suggest that “you think that a mistake was made with the blood and could the vet be so good as to check it before I leave? I would be so worried if this happened again.”
You are Nula’s advocate and no one cares as much as you do about her health. Be polite but get what you need. Always be gracious and thankful to the vet, but make this happen.
Prednisone reductions should be made at about 25-33%. They should always be preceded by a full CBC. In between these reductions you should schedule a single PCV, which should not cost you more than $15-20, to make sure she is staying stable. Put at least 2 weeks but as much as 3-4 weeks between changes. When you get to lower doses, figure out the dosage reduction over a week’s average rather than the daily dosage. For instance if is 20mg a day (10mg BID):
multiple 20 by 7 = 140mg per week
140mg * 33% = 46
140-46 = 94
94/7 = 13.5mg
So you could go down to 10mg or to 15mg. I would be apt to go to 15 mg per day. I would have, if this were me, given 10 in the morning and 5 in the evening. Your vet is always the person to ask about this. My reasoning is that dogs need that cortisol early in the day when they are active, it helps them with the stress of the day better.
When you get to much lower doses, your vet may want to try to go to an every other day dosing. This will help “wake up” the adrenal glands that have become inactive while you flooded the body with excess cortisol in the form of prednisone. There is a risk during this time that they won’t wake up as fast as we thought they should and the amount of prednisone is too low. So that is why we go very slow, to give those glands time to wake up!
The Atopica is a good drug to continue providing the immunosuppression that is required. Keeping her at doses that are comparable to what is the normal maintenance dose on the packaging for a dog with allergies.
my best
patrice